Contact your doctor if you experience serious side effects of Lipitor including: muscle wasting and muscle breakdown (rhabdomyolysis), confusion or memory problems, fever, dark urine, increased thirst or hunger, drowsiness, loss of appetite, or. yellowing of the skin or eyes (jaundice).
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The five most common adverse reactions in patients treated with LIPITOR that led to treatment discontinuation and occurred at a rate greater than placebo were: myalgia (0.7%), diarrhea (0.5%), nausea (0.4%), alanine aminotransferase increase (0.4%), and hepatic enzyme increase (0.4%). In the LIPITOR placebo-controlled clinical trial database of 16,066patients (8755 LIPITOR vs. 7311 placebo; age range 10-93 years, 39% women, 91% Caucasians, 3% Blacks, 2% Asians, 4% other)with a median treatment duration of 53 weeks, 9.7% of patients on LIPITOR and 9.5% of the patients on placebo discontinued due to adverse reactions regardless of causality.
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In IDEAL involving 8,888 subjects (age range 26-80 years, 19% women; 99.3% Caucasians, 0.4% Asians, 0.3% Blacks, 0.04% other) treated with LIPITOR80 mg/day (n=4439)or simvastatin 20-40 mg daily (n=4449), there was no difference in the overall frequency of adverse reactions or serious adverse reactions between the treatment groups during a median follow-up of 4.8 years.
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The proportions of subjects who experienced cardiovascular death were numerically smaller in the LIPITOR80 mg group (3.3%) than in the placebo group (4.1%).
Pictures of Lipitor (Atorvastatin Calcium), drug imprint information, side effects for the patient.
Atorvastatin is only part of a complete treatment program that may also include diet, exercise, and weight control. Follow your doctor's instructions very closely.
Seek emergency medical attention or call the Poison Help line at.
Psoriasis What Does a Psoriasis Rash Look Like?
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Take the medicine at the same time each day. Atorvastatin is usually taken once a day, with or without food.
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Atorvastatin is in a group of drugs called HMG CoA reductase inhibitors, or " statins.
Doctors prescribe the cholesterol drug Lipitor to prevent heart attack and stroke. Studies show the drug to be effective but also to carry serious.
Cholesterol plays a crucial role in several bodily processes that are essential to our health, but unhealthy levels of cholesterol can lead to buildup (plaque) on the walls of arteries. According to the Centers for Disease Control and Prevention, heart disease is the leading cause of death for both men and women in the U.S. This can block blood flow to the brain and heart and put people at higher risk for stroke and heart disease.
Grapefruit juice contains one or more components that inhibit CYP34A, an important enzyme found in the liver, and it can increase plasma concentrations of atorvastatin.
Symptoms related to Lipitor liver injury: Fatigue. Loss of appetite. Pain in the right upper abdomen. Dark urine. Yellowing of the skin or whites of the eyes.
A report published in JAMA Neurology showed that marked improvement or full recovery from this type of myopathy could take up to approximay 13.5 months in over half of 32 patients with aggressive early treatment including a combination of intravenous (IV) immune globulin, corticosteroids and a steroid-sparing agent. However, 10 percent of patients showed little or no clinical improvement.
Lipitor has been shown to effectively lower cholesterol in patients at an increased risk of heart disease. However, various clinical and observational studies, some conducted decades after the drug’s release onto the market, have linked the cholesterol-lowering drug to several serious side effects and complications, including the development of Type 2 diabetes.
A patient’s outlook with myopathy varies.
Lipitor (atorvastatin) is a prescription drug used to lower blood cholesterol. Common side effects are fatigue, flatulence (gas), heartburn, and constipation.
After graduating from St. Dr. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. There he was involved in research in radiation biology and received the Huisking Scholarship. He is board-certified in Internal Medicine and Rheumatology. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame.
Take the Cholesterol Quiz to understand what high cholesterol means in terms of.