Zolpidem Uses, Dosage & Side Effects


9.25.2018 by Jonathan Bootman

Zolpidem is for short-term use only. l your doctor if your insomnia symptoms do not improve, or if they get worse after using this medication for 7 to 10 nights in a row. Do not take zolpidem for longer than 4 or 5 weeks without your doctor's advice.

Never take Ambien, Edluar, or Zolpimist if you do not have a full 7 to 8 hours to sleep before being active again.

Zolpidem
Zolpidem Uses, Dosage & Side Effects

a history of depression, mental illness, or suicidal thoughts; or.

Ambien, Edluar, and Zolpimist are used to help you fall asleep when you first go to bed. Intermezzo, is used to help you fall back to sleep if you wake up in the middle of the night and then have trouble sleeping.

These symptoms may seem to be even worse than before you started taking the medicine. Insomnia symptoms may also return after you stop taking zolpidem. Call your doctor if you still have worsened insomnia after the first few nights without taking zolpidem.

The recommended doses of zolpidem are not the same in men and women, and this drug is not approved for use in children. Misuse of this medication can result in dangerous side effects.

Never take this medicine in larger amounts or for longer than prescribed.

By clicking Subscribe, I agree to the Terms & Conditions & Privacy Policy and understand that I may opt out of subscriptions at any time.

If you have taken zolpidem in the past, your doctor may direct you to take a lower dose of this medicine than you did before. In January 2013, the Food and Drug Administration (FDA) lowered the recommended dose for Ambien, Edluar, and Zolpimist.

chest pain, fast or irregular heartbeat, feeling short of breath;

Subscribe to free newsletters.

Ask your doctor how to avoid withdrawal symptoms when you stop using this medicine. Do not stop using zolpidem suddenly after long-term use, or you could have unpleasant withdrawal symptoms.

The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Available for Android and iOS devices.

Samples of this medicine purchased on the Internet have been found to contain haloperidol (Haldol), a potent antipsychotic drug with dangerous side effects. For more information, contact the U.S. Medications distributed from Internet sales may contain dangerous ingredients, or may not be distributed by a licensed pharmacy. It is dangerous to try and purchase zolpidem on the Internet or from vendors outside of the United States. Food and Drug Administration (FDA) or visit www.fda.gov/buyonlineguide.

tired feeling, loss of coordination;

nausea, constipation, diarrhea, upset stomach; or headache, muscle pain.

daytime drowsiness, dizziness, weakness, feeling "drugged" or light-headed;

Generic Name: zolpidem (zole PI dem) Brand Names: Ambien, Ambien CR, Edluar, Intermezzo, Zolpimist.

Common zolpidem side effects may include:

Report any new or worsening symptoms to your doctor, such as: depression, anxiety, aggression, agitation, confusion, unusual thoughts, hallucinations, memory problems, changes in personality, risk-taking behavior, decreased inhibitions, no fear of danger, or thoughts of suicide or hurting yourself.

Prime the spray with 1 test spray if it has not been used for longer than 14 days. Prime the spray before the first use by pumping 5 test sprays into the air, away from your face. Spray Zolpimist directly into your mouth over your tongue.

Stop taking this medicine and get emergency medical help if you have signs of an allergic reaction to zolpidem: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Zolpidem may cause a severe allergic reaction.

The immediate-release forms are Ambien, Intermezzo, Edluar, and Zolpimist, which are used to help you fall asleep. The extended-release form of zolpidem is Ambien CR, which has a first layer that dissolves quickly to help you fall asleep, and a second layer that dissolves slowly to help you stay asleep. Zolpidem is used to treat insomnia.

Overdose symptoms may include sleepiness, confusion, shallow breathing, feeling light-headed, fainting, or coma.

Other brands: Ambien, Ambien CR, Zolpimist, Intermezzo, Edluar.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use zolpidem only for the indication prescribed.

Zolpidem may cause a severe allergic reaction. Stop taking zolpidem and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Take zolpidem exactly as prescribed by your doctor. Follow all directions on your prescription label. Never take zolpidem in larger amounts, or for longer than prescribed.

Place under the tongue and allow to disintegrate compley before swallowing. For the short-term treatment of insomnia characterized by difficulties with sleep initiation: -IMMEDIATE-RELEASE TABLETS: 5 mg (women) or 5 to 10 mg (men) orally once daily immediay before bedtime Maximum dose: 10 mg orally daily -SUBLINGUAL TABLETS: EDLUAR (R): 5 mg (women) or 5 to 10 mg (men) placed under the tongue to disintegrate once a day immediay before bedtime with at least 7 to 8 hours remaining before the planned time of awakening. -ORAL SPRAY: 5 mg (women) or 5 to 10 mg (men) orally once daily immediay before bedtime Maximum dose: 10 mg orally daily COMMENTS: -The recommended duration of zolpidem therapy is generally 7 to 10 days. Use the lowest dose possible to minimize the risk of next day impairment of activities that require full alertness. The tablet should not be swallowed whole and not administered with or immediay after a meal. For insomnia characterized by difficulties with sleep onset and/or sleep maintenance (as measured by wake time after sleep onset): -EXTENDED-RELEASE TABLETS: Initial dose: 6.25 mg (women) or 6.25 to 12.5 mg (men) orally once daily immediay before bedtime Maximum dose: 12.5 mg orally once daily immediay before bedtime COMMENTS: -If the 6.25 mg dose is not effective, the dose can be increased to 12.5 mg. -Remove from the pouch just prior to dosing. -The sublingual tablet should not be swallowed or taken with water. For use as needed for the treatment of insomnia when a middle-of-the-night awakening is followed by difficulty returning to sleep if the patient has at least 4 hours of bedtime remaining before the planned time of waking: SUBLINGUAL TABLETS: -INTERMEZZO (R): Recommended and maximum dose: 1.75 mg (women) or 3.5 mg (men) SL only once per night COMMENTS: -Intermezzo (R) should be taken in bed when a patient wakes in the middle of the night and has difficulty returning to sleep. -Each metered actuation (one spray) of zolpidem tartrate oral spray delivers 5 mg of zolpidem. -If the 5 mg dose is not effective, the dose can be increased to 10 mg.

To make sure zolpidem is safe for you, l your doctor if you have: kidney disease; liver disease;

Dizziness or severe drowsiness can cause falls, accidents, or severe injuries.

Do not take Intermezzo for middle-of-the-night insomnia unless you have 4 hours of sleep time left before being active.

For the short-term treatment of insomnia characterized by difficulties with sleep initiation: -IMMEDIATE-RELEASE TABLETS, ORAL SPRAY, and EDLUAR (R) SUBLINGUAL TABLETS: Recommended dose: 5 mg orally once daily immediay before bedtime For insomnia characterized by difficulties with sleep onset and/or sleep maintenance (as measured by wake time after sleep onset): -EXTENDED-RELEASE TABLETS: Recommended dose: 6.25 mg orally once daily immediay before bedtime For use as needed for the treatment of insomnia when a middle-of-the-night awakening is followed by difficulty returning to sleep if the patient has at least 4 hours of bedtime remaining before the planned time of waking: -INTERMEZZO (R) SUBLINGUAL TABLETS: Recommended and maximum dose: Men and women over 65 years of age: 1.75 mg SL taken only once per night if the patient has at least 4 hours of bedtime remaining before the planned time of waking.

Amnesia (forgetfulness) is more common if you do not get a full 7 to 8 hours of sleep after taking zolpidem. You may be awakened before the effects of the medicine have worn off. Avoid taking zolpidem during travel, such as to sleep on an airplane.

sleep apnea (breathing stops during sleep); myasthenia gravis;

Store at room temperature away from moisture and heat. Keep the Zolpimist bottle upright when not in use. Do not freeze.

Usual Adult Dose for Insomnia:

Medically reviewed on May 1, 2017.

Many drugs can interact with zolpidem, making it less effective or increasing side effects. Not all possible interactions are listed in this medication guide. Give a list of all your medicines to any healthcare provider who treats you. l your doctor about all medicines you use, and those you start or stop using during your treatment with zolpidem. This includes prescription and over-the-counter medicines, vitamins, and herbal products.

Seek emergency medical attention or call the Poison Help line at. An overdose of zolpidem can be fatal, especially when it is taken together with other medications that can cause drowsiness.

The recommended doses of zolpidem are not the same in men and women, and this drug is not approved for use in children. Do not share this medication with another person, even if they have the same symptoms you have. Misuse of this medication can result in dangerous side effects.

feeling like you might pass out.

Insomnia melatonin, amitriptyline, lorazepam, Ativan, Ambien, temazepam, diphenhydramine, doxepin, Elavil, Lunesta, Restoril, Belsomra, eszopiclone, Ibuprofen PM, Rozerem, triazolam, Silenor, zaleplon, Sonata, doxylamine, Halcion, Dalmane, flurazepam, estazolam, More.

Wait at least 4 hours or until you are fully awake before you do anything that requires you to be awake and alert. You may still feel sleepy the morning after taking this medicine, especially if you take the extended-release tablet, or if you are a woman. Zolpidem may impair your thinking or reactions.

a history of drug or alcohol addiction.

Usual Geriatric Dose for Insomnia:

Some people using this medicine have engaged in activity such as driving, eating, walking, making phone calls, or having sex and later having no memory of the activity. If this happens to you, stop taking zolpidem and talk with your doctor about another treatment for your sleep disorder.

Zolpidem is not approved for use by anyone younger than 18 years old.

The tablets may contain lactose. You should not use this medicine if you are allergic to zolpidem. Use caution if you are sensitive to lactose.

Some people using this medicine have engaged in activity such as driving, eating, walking, making phone calls, or having sex and later having no memory of the activity. If this happens to you, stop taking zolpidem and talk with your doctor about another treatment for your sleep disorder.

Cerner Multum, Inc. Medical Disclaimer. Version: 11.01.

See also: Dosage Information (in more detail).

Zolpidem may be habit-forming. Keep the medication in a place where others cannot get to it. Selling or giving away this medicine is against the law. Never share zolpidem with another person, especially someone with a history of drug abuse or addiction.

stuffy nose, dry mouth, nose or throat irritation;

This is not a complete list of side effects and others may occur. You may report side effects to FDA at 1-800-FDA-1088. Call your doctor for medical advice about side effects.

Do not swallow the Edluar or Intermezzo tablet whole. Place the tablet under your tongue and allow it to dissolve in your mouth without water.

l your doctor if you are pregnant or plan to become pregnant. It is not known whether this medicine will harm an unborn baby.

Swallow the pill whole. Do not crush, chew, or break an Ambien CR tablet.

trouble breathing or swallowing; or.

Subscribe to receive notifications whenever new articles are published.

Ask your doctor before taking a sleeping pill, narcotic pain medicine, prescription cough medicine, a muscle relaxer, or medicine for anxiety, depression, or seizures. Taking zolpidem with other drugs that make you sleepy or slow your breathing can cause dangerous or life-threatening side effects.

Do not take this medicine if you have consumed alcohol during the day or just before bed.

Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.

The sedative effects of zolpidem may be stronger in older adults.

Since zolpidem is taken only at bedtime if needed, you are not likely to miss a dose.

Some people using this medicine have engaged in activity such as driving, eating, walking, making phone calls, or having sex and later having no memory of the activity.

Zolpidem may impair your thinking or reactions. You may still feel sleepy the morning after taking zolpidem, especially if you take the extended-release tablet, or if you are a woman. Wait until you are fully awake before you drive, operate machinery, pilot an airplane, or do anything that requires you to be awake and alert.

Find out everything you need to know about weight loss drugs in our prescription weight loss pill guide.

To view content sources and attributions, please refer to our editorial policy. provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Data sources include Micromedex (updated Sep 4th, 2018), Cerner Multum (updated Sep 4th, 2018), Wolters Kluwer (updated Sep 3rd, 2018) and others. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.

See also: Side effects (in more detail).

It affects chemicals in the brain that may be unbalanced in people with sleep problems (insomnia). Zolpidem is a sedative, also called a hypnotic.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Zolpidem can pass into breast milk and may harm a nursing baby. l your doctor if you are breast-feeding a baby.

Do not take zolpidem if you have consumed alcohol during the day or just before bed.

Stop using zolpidem and call your doctor at once if you have:

lung disease such as asthma, bronchitis, emphysema, or chronic obstructive pulmonary disease (COPD);

Your doctor will determine which form of zolpidem is best for you.

We comply with the HONcode standard for trustworthy health information - verify here.

Zolpidem